Bibliometric Trend Analysis: Turner Syndrome in Childhood

Abstract

Turner Syndrome is a genetic disorder in females caused by the partial or complete absence of one X chromosome, significantly impacting neuropsychological development during childhood. Using a bibliometric approach, this study aims to map the global research landscape on childhood TS from 1960 to 2024. Data were sourced from the Scopus database and analyzed using Publish or Perish, Microsoft Excel, and VOSviewer. Results indicate fluctuating publication trends, with a peak in 2005, driven by advancements in genetic diagnostics such as FISH and the Human Genome Project. The United States leads in research output and international collaboration. Keyword analysis identified six main research clusters: quality of life, cognitive function, metabolic disorders, puberty, and early diagnosis. However, gaps remain in research concerning the psychosocial and emotional support needs of TS patients. This study recommends a multidisciplinary approach and further exploration of socio-emotional aspects to enhance interventions and improve the quality of life for children with Turner Syndrome, especially in developing countries like Indonesia, where epidemiological data and public awareness remain limited.